Which of the following amendments was created to deny the national government the authority to make general searches and seizures of property?

The 4th Amendment is specifically designed to protect citizens from unreasonable searches and seizures by the government. It establishes the principle that law enforcement must have probable cause and obtain a warrant, supported by oath or affirmation, before searching or seizing a person's property. This safeguard aims to limit governmental power and protect individuals' privacy rights, reflecting the Founders' concerns about potential abuses of authority by the state.

The other amendments mentioned do not focus on search and seizure issues. The 14th Amendment mainly addresses citizenship and equal protection under the law, the 5th Amendment pertains to rights related to the legal process and due process, and the 6th Amendment ensures the rights of criminal defendants, such as the right to a fair trial, but does not specifically address search and seizure protections. Thus, the 4th Amendment is the clear choice for relating directly to the restrictions on the national government's authority regarding searches and seizures.