Which of the following amendments protects against self-incrimination?

The 5th Amendment provides protection against self-incrimination, a fundamental principle in the American legal system. This amendment ensures that individuals cannot be compelled to testify against themselves in criminal cases, which is often summarized by the phrase "pleading the Fifth." This protection is essential for upholding the right to a fair trial and prevents the government from coercing individuals into providing evidence that could incriminate them.

In contrast, the other amendments listed focus on different rights and protections. The 1st Amendment addresses freedoms concerning religion, expression, assembly, and the right to petition the government. The 4th Amendment protects against unreasonable searches and seizures, safeguarding individuals' privacy rights. The 6th Amendment guarantees the right to a fair trial, including the right to counsel and to confront witnesses. Each of these amendments plays a crucial role in the justice system, but only the 5th Amendment specifically addresses the issue of self-incrimination.